After a 2-week winter break (the first of its kind in the English Premier league), action returns to our screen this weekend starting with a crucial match on Friday.
Wolverhampton Wanderers host third-placed Leicester City can jump from ninth to sixth place with a win at Molineux.
Leicester City could leapfrog Manchester City into second place with a second win in three matches.
Wolves are only missing Ruben Vinagre (hamstring). Adama Traore has been passed fit after recovering from a shoulder injury.
Leicester’s Wilfred Ndidi (knee), although named in the squad, is a doubt and January signing Ryan Bennett is ineligible against his parent club.
But Wes Morgan has returned to the squad and Matty James, who is yet to make a first-team appearance this season, is building up his fitness after playing for the Under-23s.
Then on Saturday, Southampton hosts Burnley in the first match of the day
Both of Saturday’s opponents are level on 31 points and can move into the top half with victory at St Mary’s Stadium.
Southampton are targeting a fourth win in six matches, while Burnley are on a three-match unbeaten run and ahead of their hosts on goal difference.
The second game of the day sees Norwich host leaders, Liverpool
Bottom-club Norwich City will look to build on a goalless draw at Newcastle United last time out and close the seven-point gap to 17th place.
Liverpool target a 17th consecutive Premier League win as they aim to take another step towards their first Premier League title.
Sadio Mane and James Milner have trained all week and are in contention for Liverpool, who report no fresh injuries.
Xherdan Shaqiri, Nathaniel Clyne and Paul Glatzel remain the only absentees.
On Sunday, it is a double header as Aston Villa welcome Tottenham at the Villa Park.
Aston Villa, in 17th place, have lost only one of their last three matches and can move four points above the relegation zone with victory on Sunday.
Tottenham Hotspur will be aiming for a third successive win to move just a point behind fourth-placed Chelsea, who play on Monday.
Spurs have Giovani Lo Celso (groin) available for selection but Erik Lamela (thigh) will be assessed.
Harry Kane (hamstring), Juan Foyth (groin) and Moussa Sissoko (knee) continue their rehabilitation.
The last game of the weekend will see Newcastle lock horns with Arsenal at the Emirates stadium.
Arsenal and Newcastle United are level on points and will both be aiming to turn draws in victories as they prepare to meet at Emirates Stadium.
The Gunners have drawn their last four matches while Newcastle have shared the points in three of their last four, winning the other.
Sead Kolasinac (thigh), Reiss Nelson (hamstring) and Bukayo Saka (knock) have recovered from their respective injuries and are available for Arsenal.
Cedric Soares and Calum Chambers (both knee) along with Kieran Tierney (shoulder) remain sidelined while Pablo Mari has returned to full training.
Newcastle will assess Yoshinori Muto (hip) and Dwight Gayle (hamstring) while Joelinton (knock) is fit and in contention.
Andy Carroll (hip) and Jonjo Shelvey (hamstring) are ruled out.
And we can all look forward to Monday when Chelsea plays host to Manchester United at the Stamford Bridge.